Figure 1: p53-dependent induction of ASC. Figure 2: Bax is essential for cell death mediated by ASC. Figure 4: ASC protein is associated with Bax, but not with other members of the Bcl2 family. To ...

Publication showed that IC 100 suppressed retinal microglia activation by interfering with ASC speck formation, attenuating retinal inflammation, abnormal retinal vascularization, and retinal thinning ...