EARLY DIAGNOSIS of the potentially fatal disease scleroderma is essential if patients are given a chance to survive, a conference was told at the weekend. Scleroderma is an incurable and potentially ...

The drug tofacitinib was well tolerated among patients with early scleroderma, primarily affecting the protein interferon both in fibroblasts and keratinocytes. Researchers say the drug is safe and ...

In SSc, the endothelial damage is associated with characteristic microvascular changes that can easily be visualised by using a non-invasive method like nailfold capillaroscopy. Changes that may be ...

Microvascular damage and dysfunction represent the earliest morphological and functional markers of systemic sclerosis (SSc), a progressive connective tissue disease characterized by vascular ...

DESTIN, Fla. — Detection and treatment of interstitial lung disease in systemic sclerosis calls for early and aggressive action, according to data presented at the Congress of Clinical Rheumatology ...

Experts have restated that early diagnosis is key to management of scleroderma (skin hardening), an autoimmune condition of the connective tissue. Autoimmune diseases occur when the body’s tissues are ...

Researchers found a unique immune cell plays a key role in the chronic inflammation and scarring in the lungs and skin of people with scleroderma, or systemic sclerosis. After injecting mice with ...

Investigators have discovered that a biodegradable nanoparticle used in medical sutures could combat a rare, sometimes-fatal autoimmune disease. Researchers found that a unique macrophage, an immune ...

NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases Ten new research grants on scleroderma (systemic sclerosis) have been funded by the National Institute of Arthritis and ...

Scleroderma, a rare autoimmune disease characterized by skin thickening and internal organ fibrosis, has long posed significant therapeutic challenges. With limited treatment options historically ...