Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Opioids slot into opioid receptors and activate them. This sends signals to your brain to relieve pain and promote pleasure. Both endogenous opioids, which your body naturally produces, and exogenous ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

Opioid agonists are substances that activate opioid receptors in the central and peripheral nervous systems. They have several uses, from pain management to treating opioid use disorder. You have ...

Opioids remain the most potent and effective pain relievers in medicine, but they're also among the most addictive drugs that can halt a person's ability to breathe during an overdose - which can be ...

Researchers have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the 'brain in the gut.' This discovery ...

Naloxone, also known by the brand name Narcan, is one of the most important drugs in the United States’ fight against the opioid crisis. It reverses an opioid overdose nearly instantly, restarting ...