In writing about what attributes and skills qualify a scientist for a successful career in assay development for drug discovery, one characteristic that rarely gets discussed — but which is essential ...

Optimization of experimental assay design is crucial for the overall success of any drug discovery initiative. The factors that need to be considered include: selection of the most appropriate assay ...

Assays need to be specific for their research purpose, be that quantifying cellular levels of specific proteins, identification of potential new drug molecules, or quantitative measurements of levels ...

Since biological therapeutics are derived from living organisms, their manufacture and validation presents difficulties not encountered during traditional small molecule drug development. Despite the ...

Drug resistance induced by paclitaxel and carboplatin plasmatic concentrations in lung cancer cell lines. This is an ASCO Meeting Abstract from the Markers in Cancer. This abstract does not include a ...

Another major focus of my laboratory is to translate the mechanistic findings and the chemical biology tools into treatment strategies. These efforts encompass a large spectrum of activities such as ...

Lateral flow assay applications have become increasingly diverse in a post-pandemic world, and the areas of infectious disease and oncology continue to be at the forefront. In both areas, the use of ...

Approximately four months after the initial description of cases of atypical pneumonia in Wuhan, China, in December 2019, COVID-19 had become a major pandemic threat. By April 12, 2020, around half of ...

Inappropriate regulation of insulin secretion can result in extensive metabolic problems, eventually causing diabetes mellitus 1. It is extremely important that insulin is directly measured for ...

BioPorto Diagnostics and Qiagen have validated BioPorto’s generic Rapid Assay Device (gRAD) lateral flow platform on Qiagen’s ESEQuant LR3 Lateral Flow System. The firms said combining gRAD with the ...